Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.60 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.60 |
| ▸ | ITGAL | P20701 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530804 | 1.00 | ACE (0.63) | ACEALOX15ITGB2ICAM1ITGAL | |
| SCHEMBL7103470 | 0.85 | ACE (0.65) | ACEALOX15ITGB2ICAM1ITGAL | |
| SCHEMBL7103473 | 0.85 | ACE (0.65) | ACEALOX15ITGB2ICAM1ITGAL | |
| SCHEMBL231803 | 0.83 | ALOX15 (0.66) | ACEALOX15ITGB2ICAM1ITGAL | |
| SCHEMBL231804 | 0.83 | ALOX15 (0.66) | ACEALOX15ITGB2ICAM1ITGAL | |
| SCHEMBL11369419 | 0.81 | ALOX15 (0.72) | ACEALOX15ITGB2ICAM1ITGAL | |
| SCHEMBL27403392 | 0.81 | ALOX15 (0.72) | ACEALOX15ITGB2ICAM1ITGAL | |
| Benzene SCHEMBL27549804 | 0.81 | ALOX15 (0.72) | ACEALOX15ITGB2ICAM1ITGAL | |
| SCHEMBL753982 | 0.81 | ALOX15 (0.72) | ACEALOX15ITGB2ICAM1ITGAL | |
| SCHEMBL3381353 | 0.81 | ALOX15 (0.67) | ACEALOX15ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |