Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | ACE | P12821 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | APAF1 | O14727 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MPO | P05164 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | FPR2 | P25090 | 1/20 | 0.63 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381356 | 1.00 | ALOX15 (0.67) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL30782236 | 0.88 | ALOX15 (0.70) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL170878 | 0.87 | KDM4E (0.69) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL2167226 | 0.87 | ALOX15 (0.68) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL170877 | 0.87 | KDM4E (0.69) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL1755294 | 0.87 | ALOX15 (0.68) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| Konbamidin SCHEMBL6277606 | 0.86 | ALOX15 (0.64) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL5123004 | 0.86 | ALOX15 (0.67) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL5123003 | 0.86 | ALOX15 (0.67) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL1131419 | 0.86 | ALOX15 (0.67) | ALOX15ACESMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | claimed |
| WO-2022097856-A1 | PRODUCTION OF TYRIAN PURPLE CELL DYE BY USING ESCHERICHIA COLI AND DYEING METHOD USING SAME | 서울대학교산학협력단 | 2022-05-12 | — | — | WO | disclosed |
| US-20170246311-A1 | PEPTIDES FOR BINDING ALTERNATIVELY ACTIVATED MACROPHAGES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-31 | — | — | US | disclosed |
| CN-103649317-B | Therapeutic fusion proteins | SYNTAXIN LTD. (GB) | 2015-10-21 | — | — | CN | disclosed |
| CN-104328100-A | SUPPRESSION OF NEUROENDOCRINE DISEASES | SYNTAXIN LTD | 2015-02-04 | — | — | CN | disclosed |
| CN-103649317-A | Therapeutic fusion proteins | SYNTAXIN LTD | 2014-03-19 | — | — | CN | disclosed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |
| WO-1998031705-A1 | BROMO-TRYPTOPHAN CONOPEPTIDES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1998-07-23 | — | — | WO | disclosed |
| US-5734015-A | ANTIBIOTICS | MAGAININ PHARMACEUTICALS INC. (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0366549-A1 | Derivatives of adenyl cyclase and biological use thereof | INSTITUT PASTEUR (FR) | 1990-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170246311-A1 | PEPTIDES FOR BINDING ALTERNATIVELY ACTIVATED MACROPHAGES | CD14, CD209, CD68 | ALOX15 3158/4885ACE 3279/4885SMN1; SMN2 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.