Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.77 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | CDK4 | P11802 | 3/20 | 0.53 |
| ▸ | CCND1 | P24385 | 3/20 | 0.53 |
| ▸ | NOS3 | P29474 | 10/20 | 0.53 |
| ▸ | NOS1 | P29475 | 10/20 | 0.53 |
| ▸ | NOS2 | P35228 | 7/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199489 | 0.87 | HTR6 (1.00) | HTR6ADRA2ACDK4CCND1 | |
| SCHEMBL6897355 | 0.87 | HTR6 (1.00) | HTR6ADRA2ACDK4CCND1 | |
| SCHEMBL2911126 | 0.83 | HTR6 (0.92) | HTR6ADRA2ACDK4CCND1 | |
| SCHEMBL30641113 | 0.83 | HTR6 (0.92) | HTR6ADRA2ACDK4CCND1 | |
| SCHEMBL12367568 | 0.81 | NOS3 (0.56) | HTR6ADRA2ANOS3NOS1NOS2 | |
| SCHEMBL1122077 | 0.81 | NOS3 (0.57) | HTR6ADRA2ANOS3NOS1NOS2 | |
| SCHEMBL12367525 | 0.79 | NOS3 (0.52) | HTR6ADRA2ANOS3NOS1NOS2 | |
| SCHEMBL27747783 | 0.79 | NOS3 (0.52) | HTR6ADRA2ANOS3NOS1NOS2 | |
| SCHEMBL2266154 | 0.79 | NOS3 (0.56) | HTR6ADRA2ANOS3NOS1NOS2 | |
| SCHEMBL2263181 | 0.78 | NOS3 (0.51) | HTR6NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817651-A | ANALGESICS, RHEUMATIC DISEASES, ANTIINFLAMMATORY AGENTS | SANOFI (FR) | 1998-10-06 | — | — | US | disclosed |