Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.45 |
| ▸ | ITGAV | P06756 | 12/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863191 | 0.71 | KMT2A (0.47) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7997106 | 0.69 | ITGB3 (0.70) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL14367989 | 0.68 | NISCH (0.58) | ADRA2AADRA2BADRA2CPTGIR | |
| SCHEMBL2837241 | 0.68 | ITGB3 (0.54) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7753126 | 0.67 | ADRA2A (0.58) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8345145 | 0.67 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8357385 | 0.67 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL2832142 | 0.67 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL2841214 | 0.67 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| Hydrochloric Acid SCHEMBL7562956 | 0.66 | ADRA2A (0.57) | ITGB3ITGAVITGA2BITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |