Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGAV | P06756 | 6/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.40 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.40 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.40 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863151 | 0.75 | KMT2A (0.57) | KMT2ASMN1; SMN2CTSAFFAR1SIRT2 | |
| SCHEMBL7863159 | 0.75 | KMT2A (0.56) | KMT2ASMN1; SMN2CTSAFFAR1SIRT2 | |
| SCHEMBL7856510 | 0.75 | ITGB3 (0.42) | ITGB3ITGAVITGA2BFFAR1ITGB1 | |
| SCHEMBL2837241 | 0.73 | ITGB3 (0.54) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL8357385 | 0.72 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL8533029 | 0.72 | UBE2N (0.44) | CTSAITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL8530936 | 0.71 | ITGB3 (0.45) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL2832066 | 0.71 | ITGB3 (0.48) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL7500485 | 0.70 | ITGB3 (0.64) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7500489 | 0.70 | ITGB3 (0.64) | ITGB3ITGAVITGA2BITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | disclosed |