Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530976 | 0.80 | MAPT (0.56) | MAPTHSP90AA1GPR55POLBMEN1 | |
| SCHEMBL7760594 | 0.76 | MAPT (0.44) | MAPTHSP90AA1GPR55POLBMEN1 | |
| SCHEMBL3192618 | 0.76 | POLB (0.50) | MAPTHSP90AA1GPR55POLBMEN1 | |
| SCHEMBL4364196 | 0.75 | POLB (0.53) | MAPTHSP90AA1GPR55POLBMEN1 | |
| SCHEMBL21626142 | 0.74 | MAPT (0.54) | MAPTHSP90AA1GPR55POLBPDK1 | |
| SCHEMBL8509314 | 0.74 | ALDH1A1 (0.56) | MAPTHSP90AA1GPR55POLBMEN1 | |
| SCHEMBL8752414 | 0.72 | MAPT (0.48) | MAPTPOLBHDAC2MEN1KMT2A | |
| SCHEMBL28965007 | 0.72 | POLB (0.50) | MAPTHSP90AA1GPR55POLBMEN1 | |
| SCHEMBL28226450 | 0.72 | POLB (0.50) | MAPTHSP90AA1GPR55POLBMEN1 | |
| SCHEMBL7836270 | 0.72 | MAPT (0.54) | MAPTHSP90AA1GPR55POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456093-A2 | Biguanide derivatives and biocidal compositions containing them | H.B. FULLER LICENSING & FINANCING, INC. (US) | 1991-11-13 | — | — | EP | disclosed |