SCHEMBL853107

SCHEMBL853107

COC(=O)c1cc(C=O)ccc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.69
CA12 O43570 3/20 0.62
CA1 P00915 3/20 0.62
CA2 P00918 3/20 0.62
CA7 P43166 3/20 0.62
CA9 Q16790 3/20 0.62
CA14 Q9ULX7 3/20 0.62
ALDH1A1 P00352 5/20 0.56
HPGD P15428 2/20 0.56
TRIM24 O15164 1/20 0.56
ALDH5A1 P51649 1/20 0.56
ABAT P80404 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
TRIM33 Q9UPN9 1/20 0.56
RAB9A P51151 2/20 0.52
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
TSHR P16473 1/20 0.52
AOX1 Q06278 1/20 0.51
PTGS1 P23219 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16229624 0.86 PTGS2 (0.57) PTGS2CA12CA1CA2CA7
SCHEMBL358930 0.86 CA12 (0.62) PTGS2CA12CA1CA2CA7
SCHEMBL13926061 0.86 PTGS2 (0.84) PTGS2CA12CA1CA2CA7
SCHEMBL11469172 0.85 ALDH1A1 (0.58) PTGS2CA12CA1CA2CA7
SCHEMBL5033639 0.85 ALDH1A1 (0.58) PTGS2CA12CA1CA2CA7
SCHEMBL685901 0.84 PTGS2 (0.67) PTGS2CA12CA1CA2CA7
SCHEMBL28677845 0.83 ERN1 (0.56) PTGS2CA12CA1CA2CA7
SCHEMBL2608366 0.83 PTGS2 (0.65) PTGS2CA12CA1CA2CA7
SCHEMBL30362132 0.82 ALDH1A1 (0.61) PTGS2ALDH1A1HPGDTRIM24ALDH5A1
SCHEMBL18373091 0.82 ALDH1A1 (0.55) PTGS2CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119662027-A Preparation method and application of skidproof flexible silica gel with skin-friendly matte surface 东莞市莎利特新材料科技有限公司 2025-03-21 CN claimed
CN-107501392-B 1-substituted-beta-carboline-3-formyl-Trp-Trp-Thr-OBzl, and synthesis and application thereof 首都医科大学 2021-06-08 CN claimed
CN-106349148-B New indole class compound with anti-tumor metastasis and anti-inflammatory activity, synthesis and application 首都医科大学 2019-07-05 CN claimed
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US claimed
CN-106349148-A Novel indoles compound having anti-tumor metastasis activity and anti-inflammatory activity, as well as synthesis and application of novel indoles compound 首都医科大学 2017-01-25 CN claimed
CN-105315338-A LDV-modified [beta]-carboline, and preparation, nano structure, activity and application thereof UNIV CAPITAL MEDICAL SCIENCES 2016-02-10 CN claimed
CN-105273055-A RGD tetrapeptide-modified beta-carboline, preparation, activity and application thereof UNIV CAPITAL MEDICAL SCIENCES 2016-01-27 CN claimed
CN-105273054-A YIGSR-modified beta-carboline, preparation, nano-structure, activity and application thereof UNIV CAPITAL MEDICAL SCIENCES 2016-01-27 CN claimed
CN-105273047-A Amino-acid benzyl ester modified beta-carboline, activity, nanometer structure, synthesis and application UNIV CAPITAL MEDICAL SCIENCES 2016-01-27 CN claimed
CN-105237618-A Amino acid benzyl ester-modified beta-carbolines, synthesis, nanostructures, activities, and applications UNIV CAPITAL MEDICAL SCIENCES 2016-01-13 CN claimed
CN-105218636-A The β-carboline that LPNISKP modifies, its preparation, nanostructure, active and application UNIV CAPITAL MEDICAL SCIENCES 2016-01-06 CN claimed
CN-105218628-A The β-carboline that tryptophan benzyl ester is modified, its synthesis, nanostructure, active and application UNIV CAPITAL MEDICAL SCIENCES 2016-01-06 CN claimed
CN-105153277-A Beta-carboline modified by KE as well as preparation, nanostructure, activity and application of the same UNIV CAPITAL MEDICAL SCIENCES 2015-12-16 CN claimed
CN-104211699-A Beta-carboline derivatives, preparation, nano structure, antitumor activity and applications thereof UNIV CAPITAL MEDICAL SCIENCES 2014-12-17 CN claimed
EP-1879661-A1 AGENT FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-01-23 EP claimed
WO-2006119821-A1 AGENT FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed
US-12577227-B2 WDR5 inhibitors and modulators VANDERBILT UNIVERSITY (US) 2026-03-17 US disclosed
EP-4642471-A1 PLANT HYDROETHANOLIC EXTRACTS AND USES THEREOF IMMUNE & GENETICS PROTOCOLS LLC (US) 2025-11-05 EP disclosed
EP-0006735-B1 SECONDARY AMINES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE BEECHAM GROUP PLC (GB) 1983-06-15 EP disclosed
EP-0006735-A1 Secondary amines, their preparation, pharmaceutical compositions containing them and their use BEECHAM GROUP PLC (GB) 1980-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577227-B2 WDR5 inhibitors and modulators WDR1, WDR5, WDR3 PTGS2 3588/4885CA12 4481/4885CA1 3179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.