SCHEMBL8531996

SCHEMBL8531996

OC1=Cc2ccccc2C1O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
HTR2A P28223 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15535721 0.78 MAOA (0.39) MAOAMAOBMEN1GAAKMT2A
SCHEMBL4563908 0.77 MEN1 (0.35) MEN1GAAKMT2ACYP2D6
SCHEMBL28742878 0.74 MAOA (0.41) MAOAMAOBMEN1KMT2AHTR2A
SCHEMBL12629758 0.74 MAOA (0.37) MAOAMAOBMEN1KMT2AHTR2A
SCHEMBL24475199 0.74 MEN1 (0.33) MEN1GAAKMT2AHTR2A
SCHEMBL17343612 0.74 MEN1 (0.38) MEN1GAAKMT2AHTR2A
SCHEMBL680551 0.74 MEN1 (0.38) MEN1GAAKMT2AHTR2A
SCHEMBL680550 0.74 MEN1 (0.38) MEN1GAAKMT2AHTR2A
SCHEMBL30181026 0.74 MEN1 (0.38) MEN1GAAKMT2AHTR2A
SCHEMBL6237164 0.74 MEN1 (0.33) MEN1GAAKMT2AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478018-B1 MAGNESIUM DICHLORIDE-ALCOHOL ADDUCTS AND CATALYST COMPONENTS OBTAINED BASELL POLIOLEFINE SRL (IT) 2015-01-21 EP claimed
US-5811294-A Production of optically active 1,2-dihydroxyindance derivatives by asymetric assimilation ZENECA LIMITED (GB) 1998-09-22 US claimed
EP-4463534-A1 TREATMENT COMPOSITIONS WITH MODIFIED AMINO ACID MULTIMERS The Procter & Gamble Company (US) 2024-11-20 EP disclosed
CN-115583874-B Method for catalyzing asymmetric tandem reaction of internal alkyne by rhodium metal 南京林业大学 2024-05-28 CN disclosed
WO-2023137409-A1 TREATMENT COMPOSITIONS WITH MODIFIED AMINO ACID MULTIMERS THE PROCTER & GAMBLE COMPANY (US) 2023-07-20 WO disclosed
US-20230220300-A1 TREATMENT COMPOSITIONS WITH MODIFIED AMINO ACID MULTIMERS THE PROCTER & GAMBLE COMPANY 2023-07-13 US disclosed
US-10000703-B2 Catalytic fast pyrolysis process ANELLOTECH, INC. (US) 2018-06-19 US disclosed
US-20160326438-A1 CATALYTIC FAST PYROLYSIS PROCESS ANELLOTECH, INC. 2016-11-10 US disclosed
CN-102595886-A Pesticidal compositions comprising 4,5-dihydroxyindan-1-one YISSUM RES DEV CO 2012-07-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220300-A1 TREATMENT COMPOSITIONS WITH MODIFIED AMINO ACID MULTIMERS BCAT2, MTR, ASNS MAOA 288/4885MAOB 791/4885MEN1 1094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.