Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | ARG1 | P05089 | 1/20 | 0.52 |
| ▸ | ARG2 | P78540 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1088432 | 0.87 | ACHE (0.62) | ACHEHRH1KCNH2CCR3SIGMAR1 | |
| SCHEMBL10236431 | 0.83 | ACHE (0.66) | ACHEHRH1KCNH2CCR3SIGMAR1 | |
| SCHEMBL1303830 | 0.82 | HRH1 (0.56) | ACHEHRH1KCNH2CCR3SIGMAR1 | |
| SCHEMBL2485710 | 0.81 | HRH1 (0.55) | ACHEHRH1KCNH2CCR3SIGMAR1 | |
| SCHEMBL607895 | 0.81 | ACHE (0.54) | ACHEHRH1KCNH2CCR3ARG1 | |
| SCHEMBL607896 | 0.81 | ACHE (0.54) | ACHEHRH1KCNH2CCR3ARG1 | |
| SCHEMBL3272029 | 0.81 | ACHE (0.54) | ACHEHRH1KCNH2CCR3ARG1 | |
| SCHEMBL6493003 | 0.80 | LTA4H (0.64) | ACHEHRH1ARG1ARG2SIGMAR1 | |
| SCHEMBL12228499 | 0.79 | ACHE (0.60) | ACHEHRH1KCNH2CCR3SIGMAR1 | |
| SCHEMBL6362147 | 0.79 | KCNH2 (0.83) | ACHEHRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795894-A | TREATMENT OF ASTHMA AND BRONCHOSPASM | SCHERING CORPORATION (US) | 1998-08-18 | — | — | US | disclosed |