Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.56 |
| ▸ | CASR | P41180 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005868 | 0.87 | POLB (0.60) | CCR3CASRPOLBLMNAL3MBTL1 | |
| SCHEMBL27905665 | 0.81 | HTT (0.51) | POLBL3MBTL1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL27929239 | 0.80 | POLB (0.55) | CCR3CASRPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL28302839 | 0.79 | L3MBTL1 (0.48) | POLBL3MBTL1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL28302841 | 0.79 | L3MBTL1 (0.48) | POLBL3MBTL1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL444179 | 0.79 | CASR (0.74) | CCR3CASRPOLBLMNAALDH1A1 | |
| SCHEMBL17976273 | 0.78 | POLB (0.56) | POLBALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL27929193 | 0.78 | POLB (0.60) | CCR3POLBL3MBTL1ALDH1A1ITGB3 | |
| SCHEMBL8122238 | 0.77 | CASR (0.52) | CASRPOLB | |
| SCHEMBL17976487 | 0.76 | TP53 (0.59) | CCR3POLBLMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |