Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17976273 | 0.82 | POLB (0.56) | POLBKMT2AMEN1CA12CA1 | |
| SCHEMBL8532166 | 0.80 | CCR3 (0.56) | POLBCCR3ITGB3ITGAVCASR | |
| SCHEMBL7249350 | 0.78 | MARS1 (0.53) | POLBKMT2AMEN1ITGB3ITGAV | |
| SCHEMBL17976487 | 0.77 | TP53 (0.59) | POLBKMT2AMEN1CCR3EPHX1 | |
| SCHEMBL7256069 | 0.76 | EPHX1 (0.47) | POLBKMT2AMEN1ITGB3ITGAV | |
| SCHEMBL12021302 | 0.75 | KDM4E (0.46) | POLBCA12CA2CA4CA7 | |
| SCHEMBL3635005 | 0.75 | ALDH1A1 (0.47) | POLBHTTALDH1A1L3MBTL1TAS1R3 | |
| SCHEMBL6289117 | 0.75 | GOT1 (0.59) | KMT2AMEN1ITGB3ITGAVCA12 | |
| SCHEMBL28746723 | 0.75 | ALDH1A1 (0.53) | KMT2AMEN1CA1CA2HTT | |
| SCHEMBL4893227 | 0.74 | POLB (0.72) | POLBKMT2AMEN1ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183682-B | C-10 carbamido substituted artemisinin derivative and preparation method and application thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2015-10-14 | — | — | CN | disclosed |
| CN-103183682-A | C-10 carbamido substituted artemisinin derivative and preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-07-03 | — | — | CN | disclosed |