Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | CCR3 | P51677 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532166 | 0.87 | CCR3 (0.56) | POLBCCR3ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL9504011 | 0.85 | HTT (0.52) | HTT | |
| SCHEMBL444179 | 0.80 | CASR (0.74) | POLBCCR3ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL29580443 | 0.80 | HTT (0.72) | POLBALDH1A1TAS1R3TAS1R1HTT | |
| SCHEMBL9717979 | 0.80 | HTT (0.72) | POLBALDH1A1TAS1R3TAS1R1HTT | |
| SCHEMBL8010644 | 0.77 | CASR (0.51) | CCR3HTTKMT2AMEN1MAPT | |
| SCHEMBL6322814 | 0.77 | MAPT (0.60) | POLBALDH1A1TAS1R3TAS1R1MAPT | |
| SCHEMBL14559554 | 0.77 | PKM (0.49) | POLBKMT2AMEN1CASRPKM | |
| SCHEMBL948318 | 0.76 | MAPT (0.59) | POLBALDH1A1TAS1R3TAS1R1HTT | |
| SCHEMBL11028218 | 0.76 | HTT (0.77) | POLBALDH1A1TAS1R3TAS1R1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |