SCHEMBL853260

SCHEMBL853260

NCCCC[C@@H](C(=O)O)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.66
POLB P06746 4/20 0.66
KDM4E B2RXH2 1/20 0.66
TP53 P04637 1/20 0.66
GLA P06280 1/20 0.66
CYP3A4 P08684 1/20 0.66
CYP2D6 P10635 1/20 0.66
HPGD P15428 1/20 0.66
ALOX12 P18054 1/20 0.66
NFKB1 P19838 1/20 0.66
APEX1 P27695 1/20 0.66
MAPK1 P28482 1/20 0.66
HSD17B10 Q99714 1/20 0.66
GAA P10253 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.52
KMT2A Q03164 3/20 0.50
MEN1 O00255 1/20 0.50
HIF1A Q16665 1/20 0.49
DNMT1 P26358 6/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3441076 1.00 ALDH1A1 (0.66) ALDH1A1POLBKDM4ETP53GLA
SCHEMBL4604590 0.95 ALDH1A1 (0.68) ALDH1A1POLBKDM4ETP53GLA
Hydrochloric Acid SCHEMBL4604330 0.94 ALDH1A1 (0.66) ALDH1A1POLBKDM4ETP53GLA
SCHEMBL5828001 0.86 ALDH1A1 (0.68) ALDH1A1POLBKDM4ETP53GLA
SCHEMBL30587607 0.86 ALDH1A1 (0.68) ALDH1A1POLBKDM4ETP53GLA
SCHEMBL5828004 0.86 ALDH1A1 (0.68) ALDH1A1POLBKDM4ETP53GLA
SCHEMBL28775935 0.85 POLB (0.66) ALDH1A1POLBKDM4ETP53GLA
SCHEMBL9568619 0.85 MAPK1 (0.65) CYP2D6MAPK1L3MBTL1KMT2AMEN1
SCHEMBL24130616 0.84 ALDH1A1 (0.64) ALDH1A1POLBKDM4ETP53GLA
SCHEMBL9899331 0.84 POLB (0.64) ALDH1A1POLBKDM4ETP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3467096-B1 EUKARYOTIC MICROORGANISMS FOR PRODUCING LIPIDS AND ANTIOXIDANTS DSM NUTRITIONAL PRODUCTS AG (CH) 2022-01-12 EP disclosed
US-10435725-B2 Eukaryotic microorganisms for producing lipids and antioxidants DSM NUTRITIONAL PRODUCTS AG (CH) 2019-10-08 US disclosed
US-20190169660-A1 EUKARYOTIC MICROORGANISMS FOR PRODUCING LIPIDS AND ANTIOXIDANTS DSM NUTRITIONAL PRODUCTS AG (CH) 2019-06-06 US disclosed
EP-3467096-A1 EUKARYOTIC MICROORGANISMS FOR PRODUCING LIPIDS AND ANTIOXIDANTS DSM Nutritional Products AG (CH) 2019-04-10 EP disclosed
EP-3238543-B1 EUKARYOTIC MICROORGANISMS FOR PRODUCING LIPIDS AND ANTIOXIDANTS DSM NUTRITIONAL PRODUCTS AG (CH) 2019-03-20 EP disclosed
US-20170335356-A1 EUKARYOTIC MICROORGANISMS FOR PRODUCING LIPIDS AND ANTIOXIDANTS DSM NUTRITIONAL PRODUCTS AG (CH) 2017-11-23 US disclosed
EP-3238543-A1 EUKARYOTIC MICROORGANISMS FOR PRODUCING LIPIDS AND ANTIOXIDANTS DSM Nutritional Products AG (CH) 2017-11-01 EP disclosed
US-9719116-B2 Eukaryotic microorganisms for producing lipids and antioxidants DSM NUTRITIONAL PRODCUTS AG (CH) 2017-08-01 US disclosed
EP-2468847-B1 EUKARYOTIC MICROORGANISMS FOR PRODUCING LIPIDS AND ANTIOXIDANTS DSM NUTRITIONAL PRODUCTS AG (CH) 2017-03-29 EP disclosed
EP-2447356-B1 Eukaryotic microorganisms for producing lipids and antioxidants DSM NUTRITIONAL PRODUCTS AG (CH) 2016-04-20 EP disclosed
US-20070093462-A1 Multi-functional ionic liquid compositions for overcoming polymorphism and imparting improved properties for active pharmaceutical, biological, nutritional, and energetic ingredients BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA 2007-04-26 US disclosed
WO-2007044693-A2 MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS THE UNIVERSITY OF ALABAMA (US) 2007-04-19 WO disclosed
WO-2006117675-A1 FATTY ACID-BENZENEDIOL DERIVATIVES AND METHODS OF MAKING AND USING THEREOF OCEAN NUTRITION CANADA LTD. (US) 2006-11-09 WO disclosed
WO-2006109194-A2 CHROMIUM-FATTY ACID COMPOUNDS AND METHODS OF MAKING AND USING THEREOF OCEAN NUTRITION CANADA LTD. (US) 2006-10-19 WO disclosed
WO-2006078284-A2 METHODS AND COMPOSITIONS RELATED TO ANTIVIRAL THERAPY USING ALGAE AND CYANOBACTERIA UNIVERSITY OF SOUTH CAROLINA (US) 2006-07-27 WO disclosed
EP-0599444-B1 Dual action inhibitors SQUIBB & SONS INC (US) 1998-01-28 EP disclosed
EP-0783002-A2 Dual action inhibitors E.R. SQUIBB & SONS, INC. (US) 1997-07-09 EP disclosed
EP-0599444-A1 Dual action inhibitors E.R. SQUIBB & SONS, INC. (US) 1994-06-01 EP disclosed
EP-0133225-B1 PEPTIDE DERIVATIVES AND THEIR SALTS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM, PROCESS AND INTERMEDIATES FOR THEIR PRODUCTION F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1988-10-19 EP disclosed
EP-0133225-A2 Peptide derivatives and their salts, pharmaceutical preparations containing them, process and intermediates for their production F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070093462-A1 Multi-functional ionic liquid compositions for overcoming polymorphism and imparting improved properties for active pharmaceutical, biological, nutritional, and energetic ingredients SLC5A6, PNLIP, IPMK ALDH1A1 2937/4885POLB 2061/4885KDM4E 4586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.