Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625852 | 0.84 | BLM (0.47) | BLMTSHRSIGMAR1 | |
| SCHEMBL8535562 | 0.80 | DRD2 (0.38) | DRD2HTR2A | |
| SCHEMBL6642817 | 0.79 | BLM (0.52) | BLMTSHR | |
| SCHEMBL8533129 | 0.78 | DRD2 (0.45) | DRD2HTR2AHRH3SIGMAR1 | |
| SCHEMBL8199355 | 0.77 | BACE1 (0.57) | HRH3 | |
| SCHEMBL8199358 | 0.77 | BACE1 (0.57) | HRH3 | |
| SCHEMBL8199357 | 0.77 | BACE1 (0.57) | HRH3 | |
| SCHEMBL10741159 | 0.75 | HTR2A (0.50) | HTR2ASIGMAR1 | |
| SCHEMBL10649459 | 0.73 | HTR2A (0.52) | HTR2ABLMTSHR | |
| SCHEMBL19044124 | 0.73 | BLM (0.50) | DRD2BLMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |