Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437059 | 0.85 | METAP1 (0.49) | BLMTSHRLMNAMETAP1 | |
| SCHEMBL7437050 | 0.85 | METAP1 (0.49) | BLMTSHRLMNAMETAP1 | |
| SCHEMBL12362872 | 0.85 | METAP1 (0.49) | BLMTSHRLMNAMETAP1 | |
| SCHEMBL8533128 | 0.84 | DRD2 (0.49) | BLMTSHRSIGMAR1 | |
| SCHEMBL11666517 | 0.83 | DRD2 (0.50) | TSHRLMNA | |
| SCHEMBL12362871 | 0.83 | METAP1 (0.47) | BLMTSHRLMNAMETAP1 | |
| SCHEMBL11525500 | 0.80 | CACNA1G (0.49) | — | |
| SCHEMBL6795934 | 0.78 | METAP1 (0.51) | LMNAMETAP1SIGMAR1 | |
| SCHEMBL10629040 | 0.78 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL10630831 | 0.78 | SIGMAR1 (0.36) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127578-A | Diene intermediates for indantetrols | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4092318-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4044040-A | HYPERTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-08-23 | — | — | US | disclosed |