Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 3/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533170 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1PKMPOLB | |
| SCHEMBL8534807 | 0.84 | MAPK1 (0.42) | ALDH1A1TSHRMAPK1PKMPOLB | |
| SCHEMBL8534811 | 0.84 | MAPK1 (0.42) | ALDH1A1TSHRMAPK1PKMPOLB | |
| SCHEMBL8537321 | 0.82 | CCKBR (0.40) | POLBLMNACCKBRCCKARMAPT | |
| SCHEMBL8537317 | 0.82 | CCKBR (0.40) | POLBLMNACCKBRCCKARMAPT | |
| SCHEMBL8538046 | 0.81 | CCKBR (0.41) | POLBLMNACCKBRCCKARMAPT | |
| SCHEMBL8532893 | 0.81 | ALDH1A1 (0.51) | ALDH1A1PKMHSD17B10KDM4ELMNA | |
| SCHEMBL8538044 | 0.81 | CCKBR (0.41) | POLBLMNACCKBRCCKARMAPT | |
| SCHEMBL8532891 | 0.81 | ALDH1A1 (0.51) | ALDH1A1PKMHSD17B10KDM4ELMNA | |
| SCHEMBL8536820 | 0.79 | CCKBR (0.41) | PKMPOLBLMNACCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |