Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987290 | 0.90 | LMNA (0.40) | LMNAPRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL8987469 | 0.90 | LMNA (0.40) | LMNAPRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL8533788 | 0.85 | CYP3A4 (0.51) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL9998720 | 0.82 | TSHR (0.57) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL28598856 | 0.82 | TSHR (0.57) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL23878446 | 0.82 | TSHR (0.57) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL8529853 | 0.80 | ALDH1A1 (0.43) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL28062999 | 0.78 | CYP3A4 (0.60) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL8531563 | 0.77 | CYP3A4 (0.55) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL9702525 | 0.77 | CYP3A4 (0.58) | CYP3A4TSHRTDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849308-A | Method of providing surfactant properties to a cosmetic or pharmaceutical composition using alkyl N-(hydroxyalkyl) carbamates | L'OREAL (FR) | 1998-12-15 | — | — | US | disclosed |