Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987469 | 1.00 | LMNA (0.40) | LMNANPC1RAB9ASMN1; SMN2PRSS1 | |
| SCHEMBL8533291 | 0.90 | CYP3A4 (0.48) | LMNAPRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL6141476 | 0.85 | LMNA (0.47) | LMNANPC1RAB9ASMN1; SMN2PRSS1 | |
| SCHEMBL8530159 | 0.84 | LMNA (0.46) | LMNANPC1RAB9ASMN1; SMN2PRSS1 | |
| SCHEMBL8440800 | 0.82 | NPC1 (0.48) | LMNANPC1RAB9ASMN1; SMN2 | |
| Mannitol SCHEMBL8425772 | 0.81 | LMNA (0.44) | LMNAPRSS1PRSS2PRSS3MEN1 | |
| SCHEMBL8443388 | 0.80 | ACHE (0.46) | LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8440040 | 0.77 | ACHE (0.50) | LMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL8440084 | 0.77 | ACHE (0.50) | LMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL8533418 | 0.76 | ACHE (0.49) | PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587169-A | COMPRISING NONIONIC HYDROXYLATED GROUP; PROTECTIVE CREAM | L'OREAL (FR) | 1996-12-24 | — | — | US | claimed |
| US-5587169-A | COMPRISING NONIONIC HYDROXYLATED GROUP; PROTECTIVE CREAM | L'OREAL (FR) | 1996-12-24 | — | — | US | disclosed |