Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529815 | 0.80 | ADRA1A (0.46) | ADRA1ACYP1A2MTNR1AMTNR1BACHE | |
| SCHEMBL8901644 | 0.78 | CTDSP1 (0.44) | ADRA1ACYP1A2ALDH1A1HPGD | |
| SCHEMBL8528366 | 0.78 | ADRA1A (0.44) | ADRA1ACYP1A2MTNR1AMTNR1BMAPT | |
| SCHEMBL8527470 | 0.78 | CYP1A2 (0.47) | ADRA1ACYP1A2MTNR1AMTNR1BACHE | |
| SCHEMBL8527137 | 0.78 | MIF (0.45) | ADRA1ACYP1A2MTNR1AMTNR1BACHE | |
| SCHEMBL8531328 | 0.78 | ADRA1A (0.41) | ADRA1ACYP1A2MTNR1AMTNR1BACHE | |
| SCHEMBL8527142 | 0.77 | MIF (0.46) | ADRA1ACYP1A2MTNR1AMTNR1BACHE | |
| SCHEMBL8527872 | 0.77 | ADRA1A (0.40) | ADRA1ACYP1A2MTNR1AMTNR1BACHE | |
| SCHEMBL8530160 | 0.74 | ADRA1A (0.38) | ADRA1ACYP1A2MTNR1AMTNR1BACHE | |
| SCHEMBL8527998 | 0.74 | ADRA1A (0.47) | ADRA1ACYP1A2ACHEALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | claimed |
| US-5736523-A | ADMINISTERING TO THE MAMMAL SUFFERING FROM CANCER | BIOCHEM PHARMA INC. (CA) | 1998-04-07 | — | — | US | disclosed |
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | disclosed |