Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.34 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531845 | 0.83 | MEN1 (0.38) | TSHRKIF11 | |
| SCHEMBL8528275 | 0.82 | PTPN1 (0.48) | KIF11 | |
| SCHEMBL8528407 | 0.81 | PTPN1 (0.41) | FDPSKIF11PTPN5 | |
| SCHEMBL8529423 | 0.81 | KIF11 (0.38) | MMP8CA14KIF11 | |
| SCHEMBL8531404 | 0.78 | SORT1 (0.35) | FDPSSORT1 | |
| SCHEMBL8532545 | 0.77 | KIF11 (0.40) | KIF11 | |
| SCHEMBL8530829 | 0.77 | ALDH1A1 (0.40) | TSHR | |
| SCHEMBL8529288 | 0.77 | PTPN5 (0.43) | PTPN5 | |
| SCHEMBL8531385 | 0.76 | GRM4 (0.39) | KIF11 | |
| SCHEMBL8532434 | 0.76 | GRM4 (0.40) | KIF11PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |