⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293941 | 0.93 | — | — | |
| SCHEMBL8532662 | 0.93 | — | — | |
| SCHEMBL157376 | 0.86 | — | — | |
| SCHEMBL157377 | 0.86 | — | — | |
| SCHEMBL30494589 | 0.86 | — | — | |
| SCHEMBL30494611 | 0.86 | — | — | |
| SCHEMBL8532687 | 0.83 | CPT2 (0.53) | — | |
| SCHEMBL9669640 | 0.83 | — | — | |
| SCHEMBL8423638 | 0.81 | — | — | |
| SCHEMBL8533898 | 0.80 | CPT2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432984-B1 | Carbamoyl derivatives | ZENECA LTD (GB) | 1998-03-04 | — | — | EP | disclosed |
| US-5334765-A | Intermediate for leukotriene antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |
| US-5286740-A | Leukotrine antagonists; antiinflammatory agnets, antiallergens, treating asthma | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-15 | — | — | US | disclosed |
| EP-0432984-A2 | Carbamoyl derivatives | ZENECA LIMITED (GB) | 1991-06-19 | — | — | EP | disclosed |