Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202500 | 0.89 | HSD17B10 (0.46) | P2RY6HSD17B10TDP1KDM4ELMNA | |
| SCHEMBL1149469 | 0.84 | P2RY6 (0.42) | P2RY6HSD17B10KCNH2TDP1KDM4E | |
| SCHEMBL9278053 | 0.83 | P2RY6 (0.52) | P2RY6HSD17B10TDP1TSHRCA1 | |
| Edetic Acid SCHEMBL5162768 | 0.83 | MIF (0.57) | P2RY6HSD17B10TDP1KDM4ELMNA | |
| SCHEMBL7516431 | 0.83 | CA1 (0.59) | P2RY6HSD17B10CA1CA2CA4 | |
| SCHEMBL7169814 | 0.81 | P2RY6 (0.42) | P2RY6HSD17B10KCNH2TDP1CA1 | |
| SCHEMBL9310423 | 0.81 | CA1 (0.58) | P2RY6HSD17B10TDP1CA1CA2 | |
| SCHEMBL1230833 | 0.80 | HSD17B10 (0.39) | P2RY6HSD17B10TDP1KDM4ELMNA | |
| SCHEMBL15388483 | 0.80 | P2RY6 (0.40) | P2RY6HSD17B10KCNH2CA1CA2 | |
| SCHEMBL8533725 | 0.80 | P2RY6 (0.40) | P2RY6HSD17B10KCNH2TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030198598-A1 | Polypeptide derivatives | ALBERT RAINER (CH) | 2003-10-23 | — | — | US | claimed |
| EP-0436005-B1 | LABELED POLYPEPTIDE DERIVATIVES | SANDOZ LTD (CH) | 1995-03-29 | — | — | EP | claimed |
| WO-1991001144-A1 | LABELED POLYPEPTIDE DERIVATIVES | SANDOZ LTD (CH) | 1991-02-07 | — | — | WO | claimed |
| US-20030198598-A1 | Polypeptide derivatives | ALBERT RAINER (CH) | 2003-10-23 | — | — | US | disclosed |
| US-5686410-A | EPIDERMAL GROWTH FACTOR WITH CHELATING GROUP | NOVARTIS AG (CH) | 1997-11-11 | — | — | US | disclosed |
| EP-0436005-B1 | LABELED POLYPEPTIDE DERIVATIVES | SANDOZ LTD (CH) | 1995-03-29 | — | — | EP | disclosed |
| WO-1991001144-A1 | LABELED POLYPEPTIDE DERIVATIVES | SANDOZ LTD (CH) | 1991-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030198598-A1 | Polypeptide derivatives | HDGF, IGFBP1, VIP | P2RY6 3261/4885HSD17B10 4580/4885KCNH2 4746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.