Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1681792 | 0.95 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2KDM4EHPGDKMT2A | |
| SCHEMBL11686001 | 0.85 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2KDM4EHPGDKMT2A | |
| SCHEMBL8535841 | 0.83 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2KDM4EHPGDKMT2A | |
| SCHEMBL6579588 | 0.82 | HSD17B3 (0.62) | ALDH1A1SMN1; SMN2HPGDHSD17B3PARP10 | |
| SCHEMBL3141694 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2KDM4EHPGDKMT2A | |
| SCHEMBL6579608 | 0.79 | HSD17B3 (0.65) | ALDH1A1HSD17B3L3MBTL1RAB9ANPC1 | |
| SCHEMBL3027932 | 0.78 | HSD17B3 (0.66) | ALDH1A1HSD17B3L3MBTL1 | |
| SCHEMBL822848 | 0.78 | KMT2A (0.70) | ALDH1A1SMN1; SMN2KDM4EHPGDKMT2A | |
| SCHEMBL6577194 | 0.78 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KDM4EHPGDKMT2A | |
| SCHEMBL8532385 | 0.78 | HSD17B3 (0.67) | ALDH1A1SMN1; SMN2KDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |