Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686001 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EHPGDKMT2AALDH1A1 | |
| SCHEMBL4904631 | 0.83 | HSD17B3 (0.60) | SMN1; SMN2HPGDTAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL8533739 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2KDM4EHPGDKMT2AALDH1A1 | |
| SCHEMBL907469 | 0.83 | TAS1R3 (0.49) | SMN1; SMN2KDM4EHPGDTAS1R3TAS1R1 | |
| SCHEMBL8384454 | 0.80 | HSD17B3 (0.62) | TAS1R3TAS1R1HSD17B3L3MBTL1RAB9A | |
| SCHEMBL13980018 | 0.79 | TAS1R3 (0.42) | SMN1; SMN2KDM4EHPGDTAS1R3TAS1R1 | |
| SCHEMBL4902510 | 0.79 | HSD17B3 (0.64) | TAS1R3TAS1R1HSD17B3L3MBTL1HTR7 | |
| SCHEMBL1681792 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EHPGDKMT2AALDH1A1 | |
| SCHEMBL4902566 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EHPGDTAS1R3TAS1R1 | |
| SCHEMBL8536042 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EHPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |