Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26426439 | 0.85 | GPR3 (0.42) | GPR3PDE2AALOX5APFEN1KIF11 | |
| SCHEMBL29870653 | 0.85 | GPR3 (0.42) | GPR3PDE2AALOX5APFEN1KIF11 | |
| SCHEMBL28364202 | 0.81 | TRPV4 (0.48) | GPR3PDE2ACES1SCN5ASCN9A | |
| SCHEMBL29172848 | 0.80 | GPR3 (0.41) | GPR3KIF11CES1CYP1A2NPC1 | |
| SCHEMBL2720566 | 0.77 | CYP1A2 (0.42) | KIF11CYP1A2HSD17B10KDM4EMAPT | |
| SCHEMBL29641932 | 0.77 | CYP1A2 (0.42) | KIF11CYP1A2HSD17B10KDM4EMAPT | |
| SCHEMBL25468202 | 0.76 | GPR3 (0.41) | GPR3ALOX5APFEN1KIF11CES1 | |
| SCHEMBL25245867 | 0.74 | PTPN22 (0.43) | GPR3ALOX5APFEN1KIF11PTPN22 | |
| SCHEMBL519232 | 0.71 | ALDH1A1 (0.46) | GPR3PDE2AALOX5APFEN1KIF11 | |
| SCHEMBL17420607 | 0.71 | GPR3 (0.46) | GPR3PDE2AALOX5APFEN1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5725797-A | Silacyclohexane compound, a process for producing the same, and a liquid crystal composition comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |