Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536289 | 0.85 | MEN1 (0.53) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL11749787 | 0.84 | SIRT1 (0.61) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL8530243 | 0.83 | MEN1 (0.53) | ALDH1A1MEN1KMT2AMAPTSIRT1 | |
| SCHEMBL8531894 | 0.82 | SIRT1 (0.46) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL5833804 | 0.82 | KMT2A (0.50) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL8533542 | 0.81 | SLC6A4 (0.57) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL8534092 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL8530163 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL8529733 | 0.77 | MEN1 (0.54) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL8530329 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |
| EP-0396827-A1 | 2-Phenylthiobenzylamine dervivatives and acid addition salts thereof | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1990-11-14 | — | — | EP | disclosed |