Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812711 | 0.82 | PNLIP (0.49) | MEN1KMT2ARAB9AMAPK14ALDH1A1 | |
| SCHEMBL6813192 | 0.80 | MEN1 (0.52) | MEN1KMT2ATSHRLMNAMAPT | |
| SCHEMBL8533982 | 0.79 | KMT2A (0.53) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL6812369 | 0.79 | MEN1 (0.54) | MEN1KMT2ATSHRLMNAMAPT | |
| SCHEMBL6813784 | 0.76 | RAB9A (0.44) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL6812404 | 0.75 | CA12 (0.53) | MEN1KMT2AFABP4TSHRLMNA | |
| SCHEMBL6809708 | 0.74 | HDAC8 (0.53) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL6813269 | 0.73 | NPC1 (0.51) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL6813289 | 0.73 | HDAC8 (0.56) | MEN1KMT2ATSHRMAPTRAB9A | |
| SCHEMBL6813608 | 0.73 | HDAC8 (0.48) | MEN1KMT2ATSHRMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042276-A1 | THIOUREA COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING OR PREVENTING INFLAMMATORY DISEASES AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY LLC (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032433-A1 | THIOUREA AND BENZAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING OR PREVENTING INFLAMMATORY DISEASES AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |