Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | RAB9A | P51151 | 10/20 | 0.47 |
| ▸ | NPC1 | O15118 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054150 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7905128 | 0.73 | CA1 (0.51) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23212489 | 0.72 | ALDH1A1 (0.65) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL570555 | 0.70 | ALDH1A1 (1.00) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL970071 | 0.70 | ALDH1A1 (0.62) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8536020 | 0.70 | KDM4E (0.58) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10220036 | 0.70 | KDM4E (0.58) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10272059 | 0.70 | KDM4E (0.58) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9091999 | 0.70 | ALDH1A1 (0.45) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6693068 | 0.69 | SIRT1 (0.58) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780392-A | Heterocyclyl-1,3,4-thiadiazolyloxyacetamides and their use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0755395-A1 | HETEROCYCLYL-1,3,4-THIADIAZOLYLOXYACETAMIDES | BAYER AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995027711-A1 | HETEROCYCLYL-1,3,4-THIADIAZOLYLOXYACETAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-19 | — | — | WO | disclosed |