Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000252 | 0.80 | ALDH1A1 (0.72) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10054150 | 0.79 | KDM4E (0.64) | SIRT1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL10000273 | 0.76 | ALDH1A1 (0.62) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3695550 | 0.76 | TAAR1 (0.61) | SIRT1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20662904 | 0.74 | TAAR1 (0.59) | SIRT1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL23212489 | 0.73 | ALDH1A1 (0.65) | SIRT1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL29454507 | 0.73 | ALDH1A1 (0.55) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL970071 | 0.72 | ALDH1A1 (0.62) | SIRT1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL570555 | 0.72 | ALDH1A1 (1.00) | SIRT1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL13930840 | 0.71 | RAB9A (0.72) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248950-A1 | Apo ai expression accelerating agent | SHIONOGI & CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1419770-A1 | APO AI EXPRESSION ACCELERATING AGENT | SHIONOGI & CO., LTD. (JP) | 2004-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248950-A1 | Apo ai expression accelerating agent | APOB, APOL1, NR1H2 | SIRT1 2225/4885KDM4E 4259/4885ALDH1A1 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.