Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534284 | 1.00 | OPRM1 (0.40) | OPRM1ALDH1A1HSD11B1LMNAMAPT | |
| SCHEMBL8535768 | 0.88 | OPRM1 (0.40) | OPRM1ALDH1A1LMNAMAPTDRD2 | |
| SCHEMBL8535765 | 0.88 | OPRM1 (0.40) | OPRM1ALDH1A1LMNAMAPTDRD2 | |
| SCHEMBL8531154 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTKMT2ACYP1A2 | |
| SCHEMBL8531152 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTKMT2ACYP1A2 | |
| SCHEMBL8535184 | 0.83 | SLC6A4 (0.41) | SMN1; SMN2SLC6A3POLB | |
| SCHEMBL8531477 | 0.83 | SLC6A4 (0.39) | ALDH1A1MAPTKMT2AMEN1NPSR1 | |
| SCHEMBL8531475 | 0.83 | SLC6A4 (0.39) | ALDH1A1MAPTKMT2AMEN1NPSR1 | |
| SCHEMBL8535182 | 0.83 | SLC6A4 (0.41) | SMN1; SMN2SLC6A3POLB | |
| SCHEMBL8532643 | 0.82 | HCAR3 (0.34) | ALDH1A1MAPTCYP2C9CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763700-A | INSECTICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0660815-B1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECH GROUP (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0660815-A1 | PESTICIDAL FLUOROOLEFINS. | BRITISH TECNOLOGY GROUP PLC (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006741-A1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |