Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | IAPP | P10997 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534636 | 1.00 | MAPT (0.59) | MAPTLMNAKDM4EIAPPTDP1 | |
| SCHEMBL6561859 | 0.85 | CA1 (0.56) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7455794 | 0.85 | CA1 (0.56) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7677074 | 0.84 | PTPN1 (0.56) | MAPTLMNAKDM4ETDP1ALDH1A1 | |
| SCHEMBL20030390 | 0.82 | MAPT (0.40) | MAPTLMNAKDM4EIAPPTDP1 | |
| SCHEMBL14441077 | 0.82 | MAPT (0.76) | MAPTLMNAKDM4EIAPPTDP1 | |
| SCHEMBL815585 | 0.81 | MAPT (0.58) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12425723 | 0.81 | HDAC8 (0.58) | MAPTALDH1A1SMN1; SMN2TP53KMT2A | |
| SCHEMBL815583 | 0.81 | MAPT (0.58) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29523356 | 0.80 | GSK3B (0.44) | MAPTLMNAKDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873743-A2 | Use of benzylidene-ketones for dyeing keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | claimed |
| EP-2928471-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014089364-A1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS, INC (US) | 2014-06-12 | — | — | WO | disclosed |
| EP-0873743-A2 | Use of benzylidene-ketones for dyeing keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | disclosed |