Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.53 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL815585 | 1.00 | MAPT (0.58) | MAPTNPC1RAB9ALMNABCHE | |
| SCHEMBL31580406 | 0.89 | RAB9A (0.66) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL27972949 | 0.88 | MAPT (0.52) | MAPTNPC1RAB9ALMNABCHE | |
| SCHEMBL6561859 | 0.84 | CA1 (0.56) | MAPTLMNASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL7455794 | 0.84 | CA1 (0.56) | MAPTLMNASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL6265390 | 0.84 | MAPT (0.55) | MAPTNPC1RAB9ALMNABCHE | |
| SCHEMBL9341539 | 0.82 | MAPT (0.44) | MAPTNPC1RAB9ALMNABCHE | |
| SCHEMBL9341533 | 0.82 | MAPT (0.44) | MAPTNPC1RAB9ALMNABCHE | |
| SCHEMBL9006476 | 0.82 | MAPT (0.69) | MAPTNPC1RAB9ALMNABCHE | |
| SCHEMBL8534634 | 0.81 | MAPT (0.59) | MAPTNPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | claimed |
| CN-112724065-B | Synthetic method of 2-fluoroindole compound | 华侨大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-112724065-A | Synthetic method of 2-fluoroindole compound | 华侨大学 | 2021-04-30 | — | — | CN | disclosed |
| US-8759112-B2 | Multifunctional reference system for analyte determinations by fluorescence | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-8051549-B2 | Method for producing plasma display panel | PANASONIC CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| US-20110126398-A1 | METHOD FOR PRODUCING PLASMA DISPLAY PANEL | PANASONIC CORPORATION (JP) | 2011-06-02 | — | — | US | disclosed |
| CN-100483112-C | Fluorescent chemical sensor for detecting water content in organic solvent and application thereof | UNIV HUNAN (CN) | 2009-04-29 | — | — | CN | disclosed |
| US-20080014655-A1 | Multifunctional Reference System For Analyte Determinations By Fluorescence | ROCHE DIAGNOSTICS OPERATIONS, INC. (IN) | 2008-01-17 | — | — | US | disclosed |
| EP-1805503-A1 | MULTIFUNCTIONAL REFERENCE SYSTEM FOR USE IN ANALYTE DETECTION BY FLUORESCENCE | F. Hoffmann-Roche AG (CH) | 2007-07-11 | — | — | EP | disclosed |
| CN-1865935-A | Fluorescent chemical sensor for detecting water content in organic solvent and application thereof | UNIV HUNAN (CN) | 2006-11-22 | — | — | CN | disclosed |
| WO-2006045596-A1 | MULTIFUNCTIONAL REFERENCE SYSTEM FOR USE IN ANALYTE DETECTION BY FLUORESCENCE | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-04 | — | — | WO | disclosed |
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |