Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963697 | 0.85 | ERN1 (0.35) | ERN1PDCD1CD274LRRK2CYP11B1 | |
| SCHEMBL9039058 | 0.69 | ERN1 (0.34) | ERN1LRRK2CYP19A1IKBKBCTSA | |
| SCHEMBL6953958 | 0.62 | ABCB1 (0.38) | — | |
| SCHEMBL6954004 | 0.61 | SMN1; SMN2 (0.41) | CYP19A1 | |
| SCHEMBL3923741 | 0.60 | IDO1 (0.49) | ERN1CTSA | |
| SCHEMBL8552537 | 0.60 | CYP11B1 (0.43) | LRRK2CYP11B1CYP11B2CYP19A1CTSA | |
| SCHEMBL8477182 | 0.60 | CYP11B1 (0.43) | LRRK2CYP11B1CYP11B2CYP19A1CTSA | |
| SCHEMBL7793991 | 0.59 | XDH (0.53) | ERN1CTSA | |
| SCHEMBL3891577 | 0.59 | TBXAS1 (0.50) | PDCD1CD274CYP11B1CYP11B2IKBKB | |
| SCHEMBL14512889 | 0.59 | ERN1 (0.52) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |