Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 12/20 | 0.62 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.61 |
| ▸ | CCKAR | P32238 | 9/20 | 0.61 |
| ▸ | BRD4 | O60885 | 4/20 | 0.51 |
| ▸ | BRD2 | P25440 | 4/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534744 | 1.00 | CCKBR (0.62) | CCKBRSENP1CCKARBRD4BRD2 | |
| SCHEMBL8533759 | 0.92 | CCKBR (0.66) | CCKBRSENP1CCKARBRD4BRD2 | |
| SCHEMBL8533764 | 0.92 | CCKBR (0.66) | CCKBRSENP1CCKARBRD4BRD2 | |
| SCHEMBL10828856 | 0.86 | CCKBR (0.67) | CCKBRCCKARSCN9A | |
| SCHEMBL8533497 | 0.85 | CCKBR (0.64) | CCKBRSENP1CCKAR | |
| SCHEMBL7552192 | 0.83 | CCKBR (0.58) | CCKBRSENP1CCKAR | |
| SCHEMBL7552200 | 0.83 | CCKBR (0.58) | CCKBRSENP1CCKAR | |
| SCHEMBL9865538 | 0.83 | SENP1 (0.73) | CCKBRSENP1CCKARBRD4BRD2 | |
| SCHEMBL8939498 | 0.83 | SENP1 (0.73) | CCKBRSENP1CCKARBRD4BRD2 | |
| SCHEMBL7549955 | 0.82 | CCKBR (0.55) | CCKBRSENP1CCKARBRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |