Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.66 |
| ▸ | CCKAR | P32238 | 7/20 | 0.66 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.64 |
| ▸ | BRD4 | O60885 | 3/20 | 0.50 |
| ▸ | BRD2 | P25440 | 3/20 | 0.50 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533759 | 1.00 | CCKBR (0.66) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8534744 | 0.92 | CCKBR (0.62) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8534751 | 0.92 | CCKBR (0.62) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8711263 | 0.89 | SENP1 (0.79) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8711261 | 0.89 | SENP1 (0.79) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8939417 | 0.89 | SENP1 (0.79) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL7549955 | 0.88 | CCKBR (0.55) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL7549960 | 0.88 | CCKBR (0.55) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8533497 | 0.87 | CCKBR (0.64) | CCKBRCCKARSENP1 | |
| SCHEMBL10828856 | 0.87 | CCKBR (0.67) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |