Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447923 | 0.92 | CYP3A4 (0.57) | CYP3A4TSHRMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL8535525 | 0.84 | PTK2 (0.41) | CYP3A4TSHRMAPK1NPC1RAB9A | |
| SCHEMBL28716249 | 0.84 | NPC1 (0.41) | CYP3A4TSHRMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL22568390 | 0.79 | CD44 (0.48) | CYP3A4TSHRMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL10391132 | 0.78 | NPC1 (0.38) | CYP3A4TSHRMAPK1NPC1RAB9A | |
| SCHEMBL17498332 | 0.77 | CYP3A4 (0.57) | CYP3A4TSHRMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL14383996 | 0.76 | ALDH1A1 (0.36) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL6847333 | 0.75 | ALDH1A1 (0.45) | CYP3A4TSHRMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL439013 | 0.74 | CYP3A4 (0.80) | CYP3A4TSHRMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL16182536 | 0.72 | CYP3A4 (0.57) | CYP3A4TSHRMAPK1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591059-B1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | OREAL (FR) | 1998-04-15 | — | — | EP | claimed |
| EP-0591059-A1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | L'OREAL (FR) | 1994-04-06 | — | — | EP | claimed |
| JP-1210417-A | — | — | None | — | — | JP | disclosed |
| EP-0591059-B1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | OREAL (FR) | 1998-04-15 | — | — | EP | disclosed |
| US-5534036-A | Keratinous fiber dyeing methods and compositions which contain sulfated methaphenylenediamine couplers in combination with oxidation dye precursors | L'OREAL (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0591059-A1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | L'OREAL (FR) | 1994-04-06 | — | — | EP | disclosed |
| EP-0193872-B1 | DI(ALKYLTHIO) DIAMINE CHAIN EXTENDERS FOR POLYURETHANE ELASTOMERS | ETHYL CORPORATION (US) | 1993-03-31 | — | — | EP | disclosed |
| EP-0228190-B1 | RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION | ETHYL CORPORATION (US) | 1991-02-27 | — | — | EP | disclosed |
| JP-H01210417-A | PREPARATION OF MOLDED ITEM OF ELASTIC ELASTOMER | MITSUI TOATSU CHEM INC | 1989-08-24 | — | — | JP | disclosed |
| EP-0289870-A2 | Epoxy resin compositions | ETHYL CORPORATION (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0169101-B1 | PROCESS FOR PREPARING (HYDROCARBYLTHIO)CYCLIC AMINES | ETHYL CORPORATION (US) | 1988-08-24 | — | — | EP | disclosed |
| US-4760188-A | Substituted diaminotoluene | ETHYL CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |
| US-4757119-A | Diamine curing agent | ETHYL CORPORATION (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0228190-A2 | RIM polyurethanes comprising mixed diamine chain extenders and process and composition for their production | ETHYL CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4631298-A | REACTION INJECTION MOLDING POLYURETHANES | ETHYL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
| US-4595742-A | Formed by reacting polyisocyanate, an organic active hydrogen group containing compound, and a chain extender comprising an aromatic diamine | ETHYL CORPORATION (US) | 1986-06-17 | — | — | US | disclosed |
| US-4594453-A | Reacting hydrocarbyl disulfide with aromatic amine | ETHYL CORPORATION (US) | 1986-06-10 | — | — | US | disclosed |
| EP-0169101-A1 | Process for preparing (hydrocarbylthio)cyclic amines | ETHYL CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |