Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10391132 | 0.94 | NPC1 (0.38) | PTK2NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL28716249 | 0.94 | NPC1 (0.41) | PTK2NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL8534792 | 0.84 | CYP3A4 (0.48) | PTK2NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL8781023 | 0.82 | ALDH1A1 (0.38) | NPC1RAB9ACYP3A4TSHRMAPK1 | |
| SCHEMBL8447923 | 0.80 | CYP3A4 (0.57) | NPC1RAB9APOLBL3MBTL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9131059 | 0.80 | ALDH1A1 (0.37) | NPC1RAB9ACYP3A4TSHRMAPK1 | |
| SCHEMBL8536599 | 0.80 | L3MBTL1 (0.56) | NPC1POLBL3MBTL1CYP3A4TSHR | |
| SCHEMBL8444669 | 0.78 | GAA (0.60) | NPC1RAB9APOLBCYP3A4TSHR | |
| SCHEMBL13754607 | 0.78 | NPC1 (0.33) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9009886 | 0.78 | L3MBTL1 (0.54) | NPC1POLBL3MBTL1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586446-B2 | Ballistic resilient run-flat tire, kit and method thereof | ACCELLA POLYURETHANE SYSTEMS LLC (US) | 2017-03-07 | — | — | US | claimed |
| US-20160361956-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | ACCELLA POLYURETHANE SYSTEMS LLC | 2016-12-15 | — | — | US | claimed |
| EP-2819855-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | Arnco, Inc. (US) | 2015-01-07 | — | — | EP | claimed |
| WO-2013130113-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | ARNCO (US) | 2013-09-06 | — | — | WO | claimed |
| US-20130220507-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | ARNCO (US) | 2013-08-29 | — | — | US | claimed |
| EP-0591059-B1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | OREAL (FR) | 1998-04-15 | — | — | EP | claimed |
| EP-0635034-B1 | POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM | UNIROYAL CHEM CO INC (US) | 1997-07-30 | — | — | EP | claimed |
| EP-0635034-A1 | POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM. | UNIROYAL CHEM CO INC (US) | 1995-01-25 | — | — | EP | claimed |
| EP-0591059-A1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | L'OREAL (FR) | 1994-04-06 | — | — | EP | claimed |
| WO-1993021247-A1 | POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1993-10-28 | — | — | WO | claimed |
| US-9586446-B2 | Ballistic resilient run-flat tire, kit and method thereof | ACCELLA POLYURETHANE SYSTEMS LLC (US) | 2017-03-07 | — | — | US | disclosed |
| US-20160361956-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | ACCELLA POLYURETHANE SYSTEMS LLC | 2016-12-15 | — | — | US | disclosed |
| EP-2819855-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | Arnco, Inc. (US) | 2015-01-07 | — | — | EP | disclosed |
| US-8821663-B2 | Ballistic resilient run-flat tire, kit and method thereof | ARNCO (US) | 2014-09-02 | — | — | US | disclosed |
| WO-2013130113-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | ARNCO (US) | 2013-09-06 | — | — | WO | disclosed |
| US-4757119-A | Diamine curing agent | ETHYL CORPORATION (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0228190-A2 | RIM polyurethanes comprising mixed diamine chain extenders and process and composition for their production | ETHYL CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4631298-A | REACTION INJECTION MOLDING POLYURETHANES | ETHYL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0193872-A2 | Di(alkylthio) diamine chain extenders for polyurethane elastomers | ETHYL CORPORATION (US) | 1986-09-10 | — | — | EP | disclosed |
| US-4595742-A | Formed by reacting polyisocyanate, an organic active hydrogen group containing compound, and a chain extender comprising an aromatic diamine | ETHYL CORPORATION (US) | 1986-06-17 | — | — | US | disclosed |