Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 14/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535501 | 1.00 | ABCB1 (0.41) | ABCB1KCNE1KCNQ1CYP3A4MEN1 | |
| SCHEMBL8534900 | 1.00 | ABCB1 (0.41) | ABCB1KCNE1KCNQ1CYP3A4MEN1 | |
| SCHEMBL9200651 | 0.86 | ABCB1 (0.44) | ABCB1KCNE1KCNQ1KDM4E | |
| SCHEMBL9765458 | 0.85 | ABCB1 (0.43) | ABCB1KCNE1KCNQ1CYP3A4MEN1 | |
| SCHEMBL8131839 | 0.83 | ABCB1 (0.40) | ABCB1KCNE1KCNQ1CYP3A4MEN1 | |
| SCHEMBL9767073 | 0.81 | KCNE1 (0.43) | ABCB1KCNE1KCNQ1CYP3A4MEN1 | |
| SCHEMBL8535718 | 0.80 | HTR2A (0.34) | — | |
| SCHEMBL8537452 | 0.80 | TRPV1 (0.35) | KCNE1KCNQ1 | |
| SCHEMBL2471392 | 0.79 | ABCB1 (0.42) | ABCB1KDM4E | |
| SCHEMBL2471393 | 0.79 | ABCB1 (0.42) | ABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |