SCHEMBL8534955

SCHEMBL8534955

CCCOC(=O)c1ccc(NC=O)cc1S(N)(=O)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
CA1 P00915 5/20 0.41
CA2 P00918 5/20 0.41
CA9 Q16790 3/20 0.41
CA12 O43570 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
STS P08842 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CA5A P35218 1/20 0.39
RAB9A P51151 1/20 0.38
LMNA P02545 2/20 0.38
GAA P10253 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
SCN1A P35498 1/20 0.37
SCN2A Q99250 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8539079 0.90 CA1 (0.47) CA1CA2CA9CA12KDM4E
SCHEMBL8539913 0.84 CA2 (0.55) ALDH1A1CA1CA2CA9CA12
SCHEMBL7638278 0.78 CDK1 (0.42) ALDH1A1CA1CA2CA9CA12
SCHEMBL9530711 0.76 CA1 (0.50) CA1CA2CA9CA12STS
SCHEMBL7628690 0.76 CDK1 (0.54) ALDH1A1CA1CA2CA9CA12
SCHEMBL8534243 0.75 CDK1 (0.71) RAB9AGAAMAPTCYP1A2CDK1
SCHEMBL8436890 0.74 ALDH1A1 (0.67) ALDH1A1CA1CA2CA9L3MBTL1
SCHEMBL5545353 0.73 ALDH1A1 (0.60) ALDH1A1STSKDM4ERAB9ALMNA
SCHEMBL8605620 0.72 LMNA (0.38) ALDH1A1CA1CA2CA9CA12
SCHEMBL5547676 0.71 ALDH1A1 (0.64) ALDH1A1KDM4ERAB9ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0763028-B1 FORMYLAMINOPHENYLSULPHONYL UREAS, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-09-16 EP disclosed
US-5747421-A PRE- AND POSTEMERGENCE HERBICIDE SELECTIVE TO WEEDS AND NONDAMAGING TO AGRICULTURAL CROPS HOECHST SCHERING AGREVO GMBH (DE) 1998-05-05 US disclosed
EP-0763028-A1 FORMYLAMINOPHENYLSULPHONYL UREAS, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1997-03-19 EP disclosed
WO-1995032950-A1 FORMYLAMINOPHENYLSULPHONYL UREAS, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1995-12-07 WO disclosed