Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 8/20 | 0.39 |
| ▸ | CCKAR | P32238 | 5/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535225 | 1.00 | PDE10A (0.39) | PDE10ACCKBRCCKARHCRTR1HCRTR2 | |
| SCHEMBL8533830 | 0.85 | HCRTR1 (0.41) | PDE10ACCKBRCCKARHCRTR1HCRTR2 | |
| SCHEMBL8533832 | 0.85 | HCRTR1 (0.41) | PDE10ACCKBRCCKARHCRTR1HCRTR2 | |
| SCHEMBL8532893 | 0.82 | ALDH1A1 (0.51) | CCKBRCCKARLMNA | |
| SCHEMBL8532891 | 0.82 | ALDH1A1 (0.51) | CCKBRCCKARLMNA | |
| SCHEMBL8535029 | 0.82 | NPC1 (0.41) | CCKBRCCKARLMNAMAPT | |
| SCHEMBL8535030 | 0.82 | NPC1 (0.41) | CCKBRCCKARLMNAMAPT | |
| SCHEMBL8538044 | 0.81 | CCKBR (0.41) | CCKBRCCKARLMNAPOLBMAPT | |
| SCHEMBL8538046 | 0.81 | CCKBR (0.41) | CCKBRCCKARLMNAPOLBMAPT | |
| SCHEMBL8537097 | 0.80 | CCKBR (0.39) | CCKBRCCKARLMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |