Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 11/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 11/20 | 0.53 |
| ▸ | ITGAL | P20701 | 11/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464523 | 0.84 | ALDH1A1 (0.72) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL9540283 | 0.83 | MEN1 (0.70) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL8534092 | 0.83 | ALDH1A1 (0.69) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| Hydrochloric Acid SCHEMBL8530217 | 0.82 | ALDH1A1 (0.70) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL8533324 | 0.82 | ALDH1A1 (0.69) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL9540333 | 0.81 | HPGD (0.72) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL9541381 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL9541386 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL9540270 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL1399354 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MEN1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |