Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ITGB2 | P05107 | 8/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.61 |
| ▸ | ITGAL | P20701 | 8/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541381 | 1.00 | ALDH1A1 (0.66) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9464523 | 0.85 | ALDH1A1 (0.72) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8535263 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9540270 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9540333 | 0.78 | HPGD (0.72) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL5830473 | 0.76 | ITGB2 (1.00) | ALDH1A1MAPTMEN1KMT2AITGB2 | |
| SCHEMBL5830476 | 0.76 | ITGB2 (1.00) | ALDH1A1MAPTMEN1KMT2AITGB2 | |
| SCHEMBL9540283 | 0.75 | MEN1 (0.70) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8534092 | 0.75 | ALDH1A1 (0.69) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9660771 | 0.72 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012080-A1 | SUBSTITUTED DIPHENYLSULFIDES AS SEROTONIN UPTAKE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-06-24 | — | — | WO | disclosed |