Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10744068 | 0.84 | CTSK (0.40) | TDP1CA12CA14CTSKCA1 | |
| SCHEMBL15824368 | 0.83 | TDP1 (0.41) | TDP1MAOAMAOBCA12CA14 | |
| SCHEMBL6611754 | 0.83 | MAOA (0.40) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL16929983 | 0.83 | TDP1 (0.41) | TDP1MAOAMAOBCA12CA14 | |
| SCHEMBL6611508 | 0.82 | CTSK (0.41) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL6608268 | 0.81 | TDP1 (0.60) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL7715671 | 0.79 | TDP1 (0.49) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL166206 | 0.78 | CA1 (0.42) | TDP1MEN1GAAKMT2ACA2 | |
| SCHEMBL4764608 | 0.76 | CAPN1 (0.47) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL166623 | 0.75 | CA1 (0.42) | TDP1MEN1GAAKMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819133-A2 | COVALENTLY LINKED OLIGONUCLEOTIDE MINOR GROOVE BINDER CONJUGATES | EPOCH PHARMACEUTICALS, INC. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996032496-A2 | COVALENTLY LINKED OLIGONUCLEOTIDE MINOR GROOVE BINDER CONJUGATES | MICROPROBE CORPORATION (US) | 1996-10-17 | — | — | WO | disclosed |