Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608268 | 0.90 | TDP1 (0.60) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL13888625 | 0.81 | TDP1 (0.70) | TDP1MAOAMAOBKDM4EMAPK1 | |
| SCHEMBL10744068 | 0.80 | CTSK (0.40) | TDP1CA12CA1CA14 | |
| SCHEMBL16979083 | 0.80 | TDP1 (0.73) | TDP1MAOAMAOBKDM4EMAPK1 | |
| SCHEMBL7715674 | 0.80 | TDP1 (0.73) | TDP1MAOAMAOBKDM4EMAPK1 | |
| SCHEMBL8323964 | 0.79 | KDM4E (0.60) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL16929983 | 0.79 | TDP1 (0.41) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL15824368 | 0.79 | TDP1 (0.41) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL6611754 | 0.79 | MAOA (0.40) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL8535338 | 0.79 | TDP1 (0.38) | TDP1MAOAMAOBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |