Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.44 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542251 | 0.96 | KDM4E (0.54) | KDM4EALDH1A1GAALMNASIGMAR1 | |
| SCHEMBL8541455 | 0.95 | KDM4E (0.54) | KDM4EALDH1A1GAALMNASIGMAR1 | |
| SCHEMBL8536918 | 0.94 | ALDH1A1 (0.53) | KDM4EALDH1A1GAALMNASIGMAR1 | |
| SCHEMBL8535454 | 0.91 | KDM4E (0.50) | KDM4EALDH1A1GAALMNASIGMAR1 | |
| SCHEMBL8539056 | 0.91 | KDM4E (0.50) | KDM4EALDH1A1GAALMNASIGMAR1 | |
| SCHEMBL8590539 | 0.90 | ALDH1A1 (0.48) | KDM4EALDH1A1GAALMNASIGMAR1 | |
| SCHEMBL8540907 | 0.90 | ALDH1A1 (0.48) | KDM4EALDH1A1GAALMNASIGMAR1 | |
| SCHEMBL8537749 | 0.90 | ALDH1A1 (0.48) | KDM4EALDH1A1GAALMNASIGMAR1 | |
| SCHEMBL8540937 | 0.81 | SLC6A2 (0.47) | SLC6A2SLC6A4KCNH2FAAHDRD4 | |
| SCHEMBL8539540 | 0.80 | MEN1 (0.53) | KDM4EALDH1A1LMNASIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817489-A | BACTERICIDES, OR CHEMICAL INTERMEDIATES THEREOF; DRUG LIBRARIES | ISIS PHARMACEUTICALS, INC. (US) | 1998-10-06 | — | — | US | claimed |