Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537749 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL8539540 | 0.93 | MEN1 (0.53) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8535362 | 0.90 | KDM4E (0.60) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL8536070 | 0.89 | MEN1 (0.48) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8537850 | 0.89 | MEN1 (0.53) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8535566 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8542251 | 0.86 | KDM4E (0.54) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL8541455 | 0.85 | KDM4E (0.54) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL8539105 | 0.85 | KCNJ1 (0.51) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8540476 | 0.85 | KCNJ1 (0.51) | ALDH1A1KDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817489-A | BACTERICIDES, OR CHEMICAL INTERMEDIATES THEREOF; DRUG LIBRARIES | ISIS PHARMACEUTICALS, INC. (US) | 1998-10-06 | — | — | US | claimed |