Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CLPP | Q16740 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539056 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1GAATACR1L3MBTL1 | |
| SCHEMBL8540937 | 0.92 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HRH3KCNH2 | |
| SCHEMBL8535362 | 0.91 | KDM4E (0.60) | KDM4EALDH1A1GAALMNASLC6A2 | |
| SCHEMBL8542233 | 0.89 | SLC6A2 (0.43) | TACR1SLC6A2SLC6A4SLC6A3HRH3 | |
| SCHEMBL8535949 | 0.88 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HRH3 | |
| SCHEMBL8542251 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1GAALMNASLC6A2 | |
| SCHEMBL8537719 | 0.87 | SLC6A2 (0.45) | KDM4EALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8541455 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1GAALMNASLC6A2 | |
| SCHEMBL8536918 | 0.86 | ALDH1A1 (0.53) | KDM4EALDH1A1GAALMNASLC6A2 | |
| SCHEMBL8588892 | 0.83 | RORC (0.48) | KDM4EALDH1A1L3MBTL1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817489-A | BACTERICIDES, OR CHEMICAL INTERMEDIATES THEREOF; DRUG LIBRARIES | ISIS PHARMACEUTICALS, INC. (US) | 1998-10-06 | — | — | US | claimed |