SCHEMBL85354

SCHEMBL85354

CC(C)(C)C(C)(C)c1cccnn1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GOT1 P17174 1/20 0.35
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179262 0.81 GOT1 (0.38) GOT1P2RX7
SCHEMBL11125404 0.79 GOT1 (0.31) GOT1
Hydrochloric Acid SCHEMBL31617638 0.79 GOT1 (0.37) GOT1P2RX7
SCHEMBL21169013 0.78 KIF11 (0.34) GOT1
SCHEMBL20128939 0.77 GOT1 (0.35) GOT1P2RX7
SCHEMBL19872223 0.77 GOT1 (0.35) GOT1P2RX7
SCHEMBL29083684 0.77 GOT1 (0.35) GOT1P2RX7
SCHEMBL3464064 0.75
SCHEMBL23196492 0.74 GOT1 (0.33) GOT1
SCHEMBL4357788 0.74 GOT1 (0.33) GOT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0455533-B1 Process for the production of benzyl methacrylate and its aromatic ring substituted halogenated and alkylated derivatives ATOCHEM (FR) 1993-12-15 EP claimed
US-5169980-A Catalytic reaction of benzyl chloride and alkali metal methacrylate ELF ATOCHEM S.A. (FR) 1992-12-08 US claimed
EP-0455533-A1 Process for the production of benzyl methacrylate and its aromatic ring substituted halogenated and alkylated derivatives ELF ATOCHEM S.A. (FR) 1991-11-06 EP claimed
JP-5043513-A None JP disclosed
CN-116675727-A Method for synthesizing amide and/or polypeptide by taking unprotected amino acid as ammonia component 广州医科大学 2023-09-01 CN disclosed
US-8129389-B2 Substituted oxindole derivatives, medicaments containing the latter and use thereof ABBOTT GMBH & CO. KG (DE) 2012-03-06 US disclosed
US-8129389-B2 Substituted oxindole derivatives, medicaments containing the latter and use thereof ABBOTT GMBH & CO. KG (DE) 2012-03-06 US disclosed
US-20090186904-A1 Substituted Oxindole Derivatives, Medicaments Containing the Latter and Use Thereof ABBOTT GMBH & CO. KG 2009-07-23 US disclosed
US-20090186904-A1 Substituted Oxindole Derivatives, Medicaments Containing the Latter and Use Thereof ABBOTT GMBH & CO. KG 2009-07-23 US disclosed
EP-0455533-B1 Process for the production of benzyl methacrylate and its aromatic ring substituted halogenated and alkylated derivatives ATOCHEM (FR) 1993-12-15 EP disclosed
JP-H0543513-A NEW PRODUCTION METHOD OF BENZYL METHACRYLATE AND ITS DERIVATIVE WHICH ARE HALOGENATED OR ALKYLATED ON AROMATIC NUCLEUS ELF ATOCHEM SA 1993-02-23 JP disclosed
US-5169980-A Catalytic reaction of benzyl chloride and alkali metal methacrylate ELF ATOCHEM S.A. (FR) 1992-12-08 US disclosed
EP-0455533-A1 Process for the production of benzyl methacrylate and its aromatic ring substituted halogenated and alkylated derivatives ELF ATOCHEM S.A. (FR) 1991-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186904-A1 Substituted Oxindole Derivatives, Medicaments Containing the Latter and Use Thereof OXTR, AVPR2, AVPR1B GOT1 1882/4885P2RX7 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.