SCHEMBL8535646

SCHEMBL8535646

CCCC=C(C)C(=O)NN(CC)CC

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CCR2 P41597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27474148 0.89 CCR2 (0.36) KDM4EL3MBTL1CCR2
SCHEMBL8024894 0.84 KDM4E (0.34) KDM4EL3MBTL1
SCHEMBL8024895 0.84 KDM4E (0.34) KDM4EL3MBTL1
SCHEMBL858044 0.82 KDM7A (0.32) CCR2
SCHEMBL565768 0.82 KDM7A (0.32) CCR2
SCHEMBL29283244 0.79 CCR2 (0.30) CCR2
SCHEMBL27628487 0.78 CA12 (0.37) CCR2
SCHEMBL28690185 0.75 CCR2 (0.33) CCR2
SCHEMBL383606 0.75 HDAC8 (0.36) KDM4ECCR2
SCHEMBL340695 0.74 CTSD (0.38) KDM4ECCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102264902-B nucleic acid purification method 恰根有限公司 2018-06-01 CN claimed
EP-0859796-A1 AQUEOUS COMPOSITIONS THICKENED WITH ACRYLATE-BASED POLYMERIC RHEOLOGY MODIFIERS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1998-08-26 EP claimed
WO-1998006757-A1 AQUEOUS COMPOSITIONS THICKENED WITH ACRYLATE-BASED POLYMERIC RHEOLOGY MODIFIERS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1998-02-19 WO claimed
EP-0398576-B1 Multi-stage polymer particle having a hydrophobically-modified ionically soluble stage ROHM & HAAS (US) 1995-08-02 EP disclosed
US-5266646-A Thickeners for waterbase paints; viscosity stabilizers to colorants; heat resistance; blister resistance; color float; syneresis resistance ROHM AND HAAS COMPANY (US) 1993-11-30 US disclosed
EP-0444791-A1 Polymeric thickeners for aqueous-based coatings ROHM AND HAAS COMPANY (US) 1991-09-04 EP disclosed