Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535700 | 0.89 | GAA (0.52) | MAPTKMT2ASMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL55236 | 0.89 | GAA (0.52) | MAPTKMT2ASMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL9362781 | 0.83 | GAA (0.46) | MAPTSMN1; SMN2RAB9AMAPK1TP53 | |
| SCHEMBL12633039 | 0.83 | GAA (0.46) | MAPTSMN1; SMN2RAB9AMAPK1TP53 | |
| Halosulfuron SCHEMBL3374072 | 0.81 | GAA (0.44) | MAPTKMT2ASMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL8480505 | 0.80 | GAA (0.53) | MAPTKMT2ATP53GLAGAA | |
| SCHEMBL5904842 | 0.78 | RAB9A (0.46) | MAPTKMT2ASMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL9518738 | 0.77 | SMN1; SMN2 (0.47) | MAPTKMT2ASMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL8477647 | 0.77 | GAA (0.57) | MAPTKMT2ASMN1; SMN2TP53GLA | |
| SCHEMBL8477231 | 0.77 | GAA (0.52) | MAPTKMT2ATP53GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |